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An isothiocyanate that potently induces chemopreventative enzymes via Keap1-Nrf2 signaling and ARE-driven gene expression; at 15 μM, inhibits class I and II HDAC activity and suppresses tumor growth selectively in cancerous prostate epithelial cells without affecting normal cells
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Sodium butane-1-sulfonate is the sodium salt of 1-butanesulfonic acid used as a reagent in chromatographic and analytical workflows. It is water-soluble and commonly employed as a mobile phase additive to improve separation of arsenic and selenium species in HPLC and related methods. Typical specifications include a molecular weight of 160.17 g·mol⁻¹ and high purity suitable for analytical applications.
Water-soluble sodium salt suitable for aqueous mobile phases.
Facilitates chromatographic separation of arsenic and selenium compounds.
High purity for analytical and HPLC applications.
Available in small-scale lab pack sizes for research use.
Stable solid form with molecular weight 160.17 g·mol⁻¹.
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N3-TEMPO is an azide-functionalized TEMPO derivative used to introduce a nitroxide spin label via click chemistry. It participates in copper-catalyzed azide-alkyne cycloaddition (CuAAC) and strain-promoted azide-alkyne cycloaddition (SPAAC), enabling efficient conjugation and labeling of biomolecules. The compound is supplied as a high-purity solid for research applications.
Azide-functionalized TEMPO for click chemistry.
Reacts in CuAAC and SPAAC for efficient conjugation.
Introduces a stable nitroxide spin label for EPR and probing studies.
High purity suitable for research-grade applications.
Solid form for convenient storage and handling.
Useful for labeling proteins, nucleic acids, lipids, and small molecules.
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Nur77 modulator 3 is a small-molecule research compound that binds nuclear receptor Nur77 (NR4A1) and modulates its activity. It has been reported to inhibit TGF-β1-induced α-SMA and COLA1 expression and to reduce hepatic stellate cell activation and extracellular matrix deposition. Technical identifiers include CAS 2097787-75-0, formula C17H16N4S, molecular weight 308.40 g/mol, and purity 99.01%.
Modulates Nur77 activity in cellular and in vivo models.
Inhibits TGF-β1-induced α-SMA and COLA1 expression.
High purity (99.01%) suitable for biochemical and cell-based assays.
Supplied in small quantities appropriate for assay development and pilot studies.
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